Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) for PDB: 6WHA
Target5-hydroxytryptamine receptor 2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50593194(CHEMBL5184791 | US20240166618, Compound 64)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at 5-HT2AR (unknown origin) stably expressed in HEK293 cells measured after 1 hr by fluorescence based Ca2+/Fluo-4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50593194(CHEMBL5184791 | US20240166618, Compound 64)
Affinity DataKi:  2.71nMAssay Description:5-HT2A Receptor Radioligand Binding. Affinity of the test compounds for the 5-HT2A receptor was determined in radioligand binding experiments with [3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50593194(CHEMBL5184791 | US20240166618, Compound 64)
Affinity DataEC50:  2.80nMAssay Description:Agonist activity at human 5HT2A receptor transfected in HEK293T cells assessed as beta arrestin-2 recruitment measured for 2 hrs by luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50593194(CHEMBL5184791 | US20240166618, Compound 64)
Affinity DataKi:  5.79nMAssay Description:5-HT2A Receptor Radioligand Binding. Affinity of the test compounds for the 5-HT2A receptor was determined in radioligand binding experiments with [3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50593194(CHEMBL5184791 | US20240166618, Compound 64)
Affinity DataEC50:  8.60nMAssay Description:Agonist activity at human 5HT2A receptor transfected in HEK293T cells assessed as mini Galphaq recruitment measured for 2 hrs by luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50593194(CHEMBL5184791 | US20240166618, Compound 64)
Affinity DataEC50:  38nMAssay Description:Agonist activity at human 5HT2A S159A mutant transfected in HEK293T cells assessed as beta arrestin-2 recruitment measured for 2 hrs by luminescent a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50593194(CHEMBL5184791 | US20240166618, Compound 64)
Affinity DataEC50:  137nMAssay Description:Agonist activity at human 5HT2A S159A mutant transfected in HEK293T cells assessed as mini Galphaq recruitment measured for 2 hrs by luminescent assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)