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Report error Found 2 Enz. Inhib. hit(s) for PDB: 6X0T
TargetCoagulation factor XII(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM476458((2S)-1-(N,3-dicyclohexyl-D-alanyl)-4- [(4R,5S)-4-m...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human FXIIa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor XII(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM476458((2S)-1-(N,3-dicyclohexyl-D-alanyl)-4- [(4R,5S)-4-m...)
Affinity DataIC50: 17.1nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIIa can be determined using a relevant purified serin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
US Patent
PDB3D3D Structure (crystal)