Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 6X85
TargetTumor necrosis factor(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50566085(CHEMBL4779860)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of probe-5 binding to human TNFalpha (77 to 233 residues) at 1 nM by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTumor necrosis factor(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50566085(CHEMBL4779860)
Affinity DataKd:  1.90E+4nMAssay Description:Binding affinity to biotinylated human TNFalpha trimer (77 to 233 residues) expressed in Escherichia coli BL21(DE3) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)