Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 6ZL5
TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50549225(CHEMBL4750445 | US12281099, Example I-093)
Affinity DataIC50: 230nMAssay Description:Measurement of various protein-protein interactions was performed using the Alpha Screen technology developed by Perkin Elmer. Recombinant RAS protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetGTPase KRas [G12D]/Son of sevenless homolog 1 [564-1049](Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50549225(CHEMBL4750445 | US12281099, Example I-093)
Affinity DataIC50: 310nMAssay Description:The following binding partners have been used in this assay. Biotinylated KRAS G12D protein corresponding to KRAS (amino acids 1-169, with the follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)