Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 7ACD
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50611058(CHEMBL5279050)
Affinity DataIC50: 17nMAssay Description:Inhibition of METTL3 in human MOLM-13 cells assessed as reduction in m6A methylation levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50611058(CHEMBL5279050)
Affinity DataIC50: 280nMAssay Description:Inhibition of METTL3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50611058(CHEMBL5279050)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of METTL3 in human Huh-7 cells assessed as down regulation of m6A RNA level at 2 uM incubated for 72 hrs by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)