Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 7CJT
TargetHistone-lysine N-methyltransferase SETDB1(Human)
University of Sao Paulo

Curated by ChEMBL
LigandPNGBDBM50641851(CHEMBL5569118)
Affinity DataKd:  80nMAssay Description:Binding affinity N-terminal his tagged wild type human SETDB1 (190 to 410 residues ) expressed in Escherichia coli BL21 (DE3) assessed as dissociatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase SETDB1(Human)
University of Sao Paulo

Curated by ChEMBL
LigandPNGBDBM50641851(CHEMBL5569118)
Affinity DataIC50: 7.50E+5nMAssay Description:Inhibition of GST tagged human SETDB1 (190 to 410 residues ) expressed in Escherichia coli BL21 (DE3) assessed as inhibition of H3K9me2 measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase SETDB1(Human)
University of Sao Paulo

Curated by ChEMBL
LigandPNGBDBM50641851(CHEMBL5569118)
Affinity DataIC50: 9.30E+5nMAssay Description:Inhibition of GST tagged human SETDB1 (190 to 410 residues ) expressed in Escherichia coli BL21 (DE3) assessed as inhibition of H3K9me3 measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)