Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 7DXG
TargetShort transient receptor potential channel 6(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50273009(CHEMBL4129809)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as reduction in TRPC6-induced current by Whole-cell patch-clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetShort transient receptor potential channel 6(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50273009(CHEMBL4129809)
Affinity DataIC50: 7.90nMAssay Description:Antagonist activity at TRPC6 (unknown origin) assessed as inhibition of channel activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetShort transient receptor potential channel 6(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50273009(CHEMBL4129809)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as reduction in OAG-induced calcium influx after 10 mins by fluo-4/AM dye based FLIPR as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetShort transient receptor potential channel 6(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50273009(CHEMBL4129809)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human TRPC6 expressed in HEK293 cells assessed as decrease in intracellular calcium level after 24 hrs by Fluo-4 dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)