Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 7EKP
LigandPNGBDBM50393255(CHEMBL2151572)
Affinity DataKi:  4.30nMAssay Description:Binding affinity to human alpha7 nAchRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50393255(CHEMBL2151572)
Affinity DataKi:  9.98nMAssay Description:Displacement of [3H]epibatidine form human alpha7 nAchR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50393255(CHEMBL2151572)
Affinity DataEC50:  250nMAssay Description:Agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as induction of channel current at -90 mV holding potential by tw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50393255(CHEMBL2151572)
Affinity DataEC50:  340nMAssay Description:Displacement of [3H]-MLA from human alpha7 nAChR expressed in xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50393255(CHEMBL2151572)
Affinity DataEC50:  390nMAssay Description:Partial agonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes by voltage clamp electrophysiological methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)