Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) for PDB: 7JKZ
TargetBromodomain-containing protein 4(Human)
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50640768(CHEMBL5589873)
Affinity DataKd:  8.90nMAssay Description:Binding affinity to his6-tagged human BRD4 BD1 (44 to 168 residues) expressed in Escherichia coli Rossetta BL21 (DE3) cells assessed as dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50640768(CHEMBL5589873)
Affinity DataKd:  10nMAssay Description:Binding affinity to BRD4 BD1 (unknown origin) assessed as dissociation constant by BROMOscan analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50640768(CHEMBL5589873)
Affinity DataIC50: 12nMAssay Description:Inhibition of N-terminal his6-tagged human BRD4 BD1 (44 to 168 residues) expressed in Escherichia coli Rossetta BL21 (DE3) cells incubated for 15 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50640768(CHEMBL5589873)
Affinity DataKd:  826nMAssay Description:Binding affinity to BRD4 BD2 (unknown origin) assessed as dissociation constant by BROMOscan analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50640768(CHEMBL5589873)
Affinity DataKd:  1.65E+3nMAssay Description:Binding affinity to his-tagged human BRD4 BD2 assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50640768(CHEMBL5589873)
Affinity DataIC50: 3.11E+3nMAssay Description:Inhibition of N-terminal his6-tagged human BRD4 BD2 incubated for 15 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)