Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 7LAN
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM434866(US10577383, Example 26 | 7-[(3R,4S,6S,10R)-4-Benzy...)
Affinity DataIC50: 5nMAssay Description:Inhibition of MPO (unknown origin) chlorination activity incubated for 10 mins followed by NaCl addition by aminophenyl fluorescein assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM434866(US10577383, Example 26 | 7-[(3R,4S,6S,10R)-4-Benzy...)
Affinity DataIC50: 50nMAssay Description:MPO chlorination activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Aminophenyl fluorescein (APF, Invitrogen Cat. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM434866(US10577383, Example 26 | 7-[(3R,4S,6S,10R)-4-Benzy...)
Affinity DataIC50: 50nMAssay Description:MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen Cat. #A12222) which can...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
US Patent
PDB3D3D Structure (crystal)