Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 7MSA
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50572808(Giredestrant | Gdc-9545 | RO-7197597 | RO7197597 |...)
Affinity DataIC50: 0.0500nMAssay Description:Antagonist activity at estrogen receptor in human T47D cells incubated for 18 hrs by ultra high sensitivity luminescence reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50572808(Giredestrant | Gdc-9545 | RO-7197597 | RO7197597 |...)
Affinity DataEC50:  0.203nMAssay Description:All of the exemplary Formula I compounds in Tables 1 and 2 were tested for binding to ERa (Estrogen Receptor alpha) and biological activity according...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)