Affinity DataIC50: 55nMAssay Description:WEE1 (Thermo Fisher, Cat #PR7373A) protein in buffer (50 mM HEPES pH 7.5, 10 mM MgCl2, 1 mM EGTA, 0.01% Brij-35) at 15 nM) in different concentration...More data for this Ligand-Target Pair
Affinity DataIC50: 567nMAssay Description:Inhibition of Wee1 in human U2OS cells assessed as reduction in CDK1 phosphorylation measured for 1 hr by Western blot analysisMore data for this Ligand-Target Pair

3D Structure (crystal)