Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) for PDB: 7Q6Z
TargetProtein-cysteine N-palmitoyltransferase HHAT(Human)
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50620903(CHEMBL5421720)
Affinity DataKi:  38nMAssay Description:Inhibition of HHAT (unknown origin) assessed as inhibition constant by Pal-CoA Competitive assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein-cysteine N-palmitoyltransferase HHAT(Human)
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50620903(CHEMBL5421720)
Affinity DataIC50: 76nMAssay Description:Inhibition of HHAT in human HEK293a SHH+ cells assessed as inhibition SHH-YnPal tagging measured after 7 hrs by cell-based tagging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein-cysteine N-palmitoyltransferase HHAT(Human)
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50620903(CHEMBL5421720)
Affinity DataIC50: 76nMAssay Description:Inhibition of HHAT in human HEK293a SHH+ cells assessed as inhibition SHH-YnPal tagging measured after 7 hrs by cell-based tagging assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein-cysteine N-palmitoyltransferase HHAT(Human)
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50620903(CHEMBL5421720)
Affinity DataEC50:  99nMAssay Description:Inhibition of HHAT in human HEK293a SHH+ cells incubated with compound for 24 hrs followed by transferred into SHH-Light2 cells cellular incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein-cysteine N-palmitoyltransferase HHAT(Human)
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50620903(CHEMBL5421720)
Affinity DataIC50: 750nMAssay Description:Inhibition of human recombinant HHAT using SHH-FAM peptide as substrate for 30 mins by acylation coupled lipophilic induction of polarization (acyl-c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProtein-cysteine N-palmitoyltransferase HHAT(Human)
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50620903(CHEMBL5421720)
Affinity DataIC50: 750nMAssay Description:Inhibition of HHAT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)