Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) for PDB: 7T2G
TargetMu-type opioid receptor(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50474150(CHEMBL58362)
Affinity DataKi:  0.0100nMAssay Description:Binding affinity to mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Guinea pig)
Chiba University

Curated by ChEMBL
LigandPNGBDBM50474150(CHEMBL58362)
Affinity DataKi:  0.0871nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor mu 1 using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50474150(CHEMBL58362)
Affinity DataIC50: 0.282nMAssay Description:Inhibition of mu opioid receptor (unknown origin) in presence of DPDPE by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Mouse)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50474150(CHEMBL58362)
Affinity DataKi:  0.75nMAssay Description:Displacement of [125I]-IBNtxA from mouse mu opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50474150(CHEMBL58362)
Affinity DataEC50:  1.70nMAssay Description:Inhibition of mu opioid receptor (unknown origin) in presence of DAMGO by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Mouse)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50474150(CHEMBL58362)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at mouse mu opioid receptor-1 expressed in CHO cell membranes assessed as [35S]GTPgammaS binding incubated for 60 mins by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50474150(CHEMBL58362)
Affinity DataEC50:  1.70nMAssay Description:Inhibition of mu opioid receptor (unknown origin) in presence of DPDPE by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50474150(CHEMBL58362)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of mu opioid receptor (unknown origin) in presence of DAMGO by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50474150(CHEMBL58362)
Affinity DataIC50: 34nMAssay Description:Inhibition of DAMGO-induced beta-arrestin-2 recruitment at mu opioid receptor-1 (unknown origin) expressed in CHO cells preincubated for 30 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)