Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 7T4U
TargetcGMP-dependent protein kinase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50598792(CHEMBL5188380)
Affinity DataEC50:  290nMAssay Description:Activation of cGMP induced partially activated state recombinant PKG1alpha (unknown origin) using Glass-tide peptide substrate incubated for 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcGMP-dependent protein kinase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50598792(CHEMBL5188380)
Affinity DataEC50:  3.20E+3nMAssay Description:Activation of cGMP induced partially activated state recombinant human full length N-terminal His tagged PKG1beta expressed in Baculovirus infected S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcGMP-dependent protein kinase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50598792(CHEMBL5188380)
Affinity DataEC50:  3.33E+4nMAssay Description:Activation of PKG1alpha in human HEK293 cells stably expressing VASP assessed as VSAP phosphorylation at Ser 239 incubated for 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcGMP-dependent protein kinase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50598792(CHEMBL5188380)
Affinity DataEC50:  1.68E+5nMAssay Description:Activation of basal state recombinant PKG1alpha (unknown origin) using Glass-tide peptide substrate incubated for 30 mins followed by ATP addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)