Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 7T6S
TargetN-formyl peptide receptor 2(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM21692(1-(4-chlorophenyl)-3-[1-methyl-5-(1-methylethyl)-3...)
Affinity DataEC50:  41nMAssay Description:Biased agonist activity at human FPR2 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetN-formyl peptide receptor 2(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM21692(1-(4-chlorophenyl)-3-[1-methyl-5-(1-methylethyl)-3...)
Affinity DataEC50:  44nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetN-formyl peptide receptor 2(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM21692(1-(4-chlorophenyl)-3-[1-methyl-5-(1-methylethyl)-3...)
Affinity DataEC50:  44nMAssay Description:Activity at human FPRL1-mediated calcium mobilization in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetN-formyl peptide receptor 2(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM21692(1-(4-chlorophenyl)-3-[1-methyl-5-(1-methylethyl)-3...)
Affinity DataEC50:  95nMAssay Description:Biased agonist activity at human FPR2 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)