Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 7T78
TargetHexokinase-4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585812(CHEMBL5091943)
Affinity DataEC50:  38nMAssay Description:Activation of recombinant full length human liver glucokinase expressed in Escherichia coli incubated for 10 mins by plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHexokinase-4(Mouse)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585812(CHEMBL5091943)
Affinity DataEC50:  42nMAssay Description:Activation of recombinant mouse full length liver glucokinase expressed in Escherichia coli incubated for 10 mins in presence of 12 mM glucose by pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHexokinase-4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585812(CHEMBL5091943)
Affinity DataEC50:  64nMAssay Description:Activation of recombinant human full length liver glucokinase expressed in Escherichia coli incubated for 10 mins in presence of 5 mM glucose by plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHexokinase-4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585812(CHEMBL5091943)
Affinity DataIC50: 122nMAssay Description:Displacement of fluorescent labeled derivative from recombinant human hepatic glucokinase incubated for 30 mins in presence of 12 mM glucose by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHexokinase-4(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50585812(CHEMBL5091943)
Affinity DataEC50:  185nMAssay Description:Activation of recombinant human full length liver glucokinase expressed in Escherichia coli incubated for 10 mins in presence of 2 mM glucose by plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)