Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 7T7L
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50595368(CHEMBL5191615)
Affinity DataIC50: 100nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50595368(CHEMBL5191615)
Affinity DataKd:  790nMAssay Description:Binding affinity to human G9a (913 to 1193 residues) assessed as dissociation constant by isothermal titration calorimetry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50595368(CHEMBL5191615)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human G9a (913 to 1193 residues) using H3 peptide as substrate measured upto 45 mins in presence of SAM cofactorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)