Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 7V18
TargetCoagulation factor XI(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50598724(CHEMBL5170592)
Affinity DataKi:  0.170nMAssay Description:Inhibition of human coagulation factor XIa assessed as inhibition constant using 5FAM-Lys.Leu-Thr-Arg-Ala-Glu-Thr-Val-Lys(5Tamra)-amide as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor XI(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50598724(CHEMBL5170592)
Affinity DataIC50: 0.330nMAssay Description:Inhibition of human plasma coagulation factor XIa using Boc-Glu(OBzl)-Ala-Arg-MCA as substrate preincubated for 5 to 15 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)