Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 7WMV
TargetSodium/glucose cotransporter 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM176714(US9688710, 136 N-(1-((2-(dimethylamino)ethyl)amino...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human HA-tagged SGLT1 expressed in HEK293 cells assessed as decrease in [14C]-AMG uptake measured after 1 to 2 hrs by scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 1(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM176714(US9688710, 136 N-(1-((2-(dimethylamino)ethyl)amino...)
Affinity DataIC50: 10nMpH: 7.3Assay Description:Human sodium/glucose co-transporter type 1 (SGLT1; accession number NP_000334; GI: 4507031) was cloned into pIRESpuro2 vector for mammalian expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
US Patent
PDB3D3D Structure (crystal)