Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 8A9I
LigandPNGBDBM50630171(CHEMBL5400057 | US12247029, Entry 11)
Affinity DataIC50: 95nMAssay Description:Inhibition of recombinant GST-tagged human PI3KC2alpha (142 to 1412 residues) expressed in baculovirus expression system using PI lipid kinase as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50630171(CHEMBL5400057 | US12247029, Entry 11)
Affinity DataIC50: 100nMAssay Description:ADP-Glo kinase assay was performed as described by the manufacturer's protocol. Briefly, the kinase assay was performed with a 5 mixture of liver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
LigandPNGBDBM50630171(CHEMBL5400057 | US12247029, Entry 11)
Affinity DataIC50: 100nMAssay Description:Inhibition of PI3KC2alpha deltaN domain (unknown origin) preincubated for 5 mins followed by substrate addition and measured after 20 mins in the pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)