Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) for PDB: 8BLB
Target5-hydroxytryptamine receptor 3A(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50400902(CHEMBL2204360 | vortioxetine hydrobromide | 1-(2-(...)
Affinity DataIC50: 0.180nMAssay Description:Binding affinity to rat 5HT3A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 3A(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50400902(CHEMBL2204360 | vortioxetine hydrobromide | 1-(2-(...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity to human 5HT3A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 3A(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50400902(CHEMBL2204360 | vortioxetine hydrobromide | 1-(2-(...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity to human 5-HT3R assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 3A(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50400902(CHEMBL2204360 | vortioxetine hydrobromide | 1-(2-(...)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at human 5HT3A receptor expressed in xenopus oocytes assessed as inhibition of 5HT-induced effect by electrophysiological methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 3A(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50400902(CHEMBL2204360 | vortioxetine hydrobromide | 1-(2-(...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 3A(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50400902(CHEMBL2204360 | vortioxetine hydrobromide | 1-(2-(...)
Affinity DataKi:  230nMAssay Description:Binding affinity to rat 5HT3A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 3A(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50400902(CHEMBL2204360 | vortioxetine hydrobromide | 1-(2-(...)
Affinity DataEC50:  2.10E+3nMAssay Description:Agonist activity at human 5HT3A receptor expressed in xenopus oocytes by electrophysiological methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)