Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 8C4W
TargetAutotaxin(Human)
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50641342(CHEMBL5569276)
Affinity DataIC50: 810nMAssay Description:Inhibition of recombinant human ATXgamma using LPC16:0 as substrate measured every 60 sec for 50 mins by choline release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50641342(CHEMBL5569276)
Affinity DataIC50: 820nMAssay Description:Inhibition of recombinant human ATXbeta using LPC18:1 as substrate measured every 60 sec for 50 mins by choline release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50641342(CHEMBL5569276)
Affinity DataIC50: 880nMAssay Description:Inhibition of recombinant human ATXbeta using LPC16:0 as substrate measured every 60 sec for 50 mins by choline release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50641342(CHEMBL5569276)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of recombinant human ATXgamma using LPC18:1 as substrate measured every 60 sec for 50 mins by choline release assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)