Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 8CJL
TargetTryptophan 5-hydroxylase 1(Human)
Leibniz-Fmp

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630639BDBM50630639(CHEMBL5404510)
Affinity DataKd:  3.20nMAssay Description:Binding affinity to THP1 (unknown origin) assessed as equilibrium dissociation constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTryptophan 5-hydroxylase 1(Human)
Leibniz-Fmp

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50630639BDBM50630639(CHEMBL5404510)
Affinity DataIC50: 952nMAssay Description:Inhibition of THP1 in human serotonergic BON cells assessed as reduced the intracellular serotonin levels incubated for 72 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)