Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) for PDB: 8DD5
TargetHistone acetyltransferase KAT6A [507-778](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 580669BDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  0.350nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compound stocks 3-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetHistone acetyltransferase KAT6A [507-778](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 580669BDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  0.380nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compound stocks 3-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetHistone acetyltransferase KAT6A [507-778](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 580669BDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  0.460nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compound stocks 3-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetHistone acetyltransferase KAT6A [507-778](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 580669BDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  0.660nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compound stocks 3-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetHistone acetyltransferase KAT6A [507-778](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 580669BDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  0.740nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compound stocks 3-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetHistone acetyltransferase KAT6A [507-778](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 580669BDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  0.75nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compound stocks 3-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetHistone acetyltransferase KAT6A [507-778](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 580669BDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  0.800nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compound stocks 3-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetHistone acetyltransferase KAT6A [507-778](Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 580669BDBM580669(US11492346, Example 9 | US11492346, Example 90 | U...)
Affinity DataKi:  0.830nMAssay Description:A. Compound preparation 1. Prepare 10 mM stock solutions in 100% DMSO from solid material 2. Serial dilute 10 mM, 1 mM or 0.1 mM compound stocks 3-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetHistone acetyltransferase KAT6A(Human)
Isosterix

US Patent
LigandChemical structure of BindingDB Monomer ID 580748BDBM580748(US11492346, Example 90 | US20250122182, Example 98...)
Affinity DataIC50: 1nMAssay Description:The Kat6a inhibitory activity of test compounds was determined using an Alpha Screen-based detection method. The assay reactions were conducted in a ...More data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)