Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 8DKB
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616146(CHEMBL5411016)
Affinity DataKi:  63nMAssay Description:Binding affinity to human his-tagged recombinant YEATS4 expressed in Escherichia coli assessed as inhibition constant using biotin tagged lysine 27-c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616146(CHEMBL5411016)
Affinity DataKd:  80nMAssay Description:Binding affinity to YEATS4 (unknown origin) assessed as dissociation constant by isothermal calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616146(CHEMBL5411016)
Affinity DataIC50: 290nMAssay Description:Inhibition of N-terminal nanoLuc-tagged YEATS4 in HEK293T cells co-transfected with C-terminal halo-tagged histone 3.3 incubated for 24 hrs in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetYEATS domain-containing protein 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50616146(CHEMBL5411016)
Affinity DataKd:  530nMAssay Description:Binding affinity to C-terminal biotin-tagged YEATS4 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)