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Found
1
Enz. Inhib. hit(s) for PDB:
8E24
Target
DNA polymerase theta
(Human)
Repare Therapeutics
Curated by
ChEMBL
Ligand
BDBM50591024
(CHEMBL5188048)
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Affinity Data
IC50: 1.40nM
Assay Description:
Inhibition of human DNA polymerase theta pol domain (1819 to 2590 residues) expressed in Escherichia coli BL21 (DE3) cells preincubated for 15 mins f...
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Target Info
PDB
KEGG
UniProtKB/SwissProt
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Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
6/20/2023
Entry Details
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PubMed
PDB
3D Structure (crystal)
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