Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 8G45
TargetHistone deacetylase 6(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50627659(CHEMBL5410606)
Affinity DataKd:  80nMAssay Description:Binding affinity to N-terminal Avi-tagged and C-terminal His6-tagged HDAC6 UBD (1109 to 1215 residues) (unknown origin) expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50627659(CHEMBL5410606)
Affinity DataKd:  84nMAssay Description:Binding affinity to N-terminal Avi-tagged and C-terminal His6-tagged HDAC6 UBD (1109 to 1215 residues) (unknown origin) expressed in Escherichia coli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50627659(CHEMBL5410606)
Affinity DataKd:  95nMAssay Description:Binding affinity to N-terminal His-tagged HDAC6 UBD (1109 to 1213 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50627659(CHEMBL5410606)
Affinity DataKd:  260nMAssay Description:Binding affinity to full length HDAC6 (1 to 1215 residues) (unknown origin) expressed in Sf9 cells assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50627659(CHEMBL5410606)
Affinity DataKd:  440nMAssay Description:Binding affinity to full length HDAC6 (1 to 1215 residues) (unknown origin) expressed in Sf9 cells using N-terminal FITC-labeled RLRGG substrate incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)