Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 8GXP
TargetNuclear receptor ROR-gamma(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM23208(cid_64971 | CHEMBL269277 | (1R,2R,5S,8R,9R,10R,13R...)
Affinity DataIC50: 2.20E+3nMAssay Description:Antagonist activity at ROR-gamma LBD (unknown origin) using biotinylated SRC1-2 as substrate preincubated for 60 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNuclear receptor ROR-gamma(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM23208(cid_64971 | CHEMBL269277 | (1R,2R,5S,8R,9R,10R,13R...)
Affinity DataKd:  2.70E+3nMAssay Description:Binding affinity to CM5 chip-immobilized recombinant ROR-gamma LBD (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNuclear receptor ROR-gamma(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM23208(cid_64971 | CHEMBL269277 | (1R,2R,5S,8R,9R,10R,13R...)
Affinity DataKd:  3.39E+3nMAssay Description:Binding affinity to ROR-gamma LBD (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)