Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 8H78
Target72 kDa type IV collagenase(Human)
Taisho Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50616392(CHEMBL5412341)
Affinity DataKi:  0.0340nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-N2 as substrate preincubated for 10 to 15 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
Target72 kDa type IV collagenase(Human)
Taisho Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50616392(CHEMBL5412341)
Affinity DataIC50: 0.0340nMAssay Description:Inhibition of human recombinant MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-N2 as substrate preincubated for 5 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
Target72 kDa type IV collagenase(Human)
Taisho Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50616392(CHEMBL5412341)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of human recombinant MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-N2 as substrate preincubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
Target72 kDa type IV collagenase(Human)
Taisho Pharmaceutical Co.

Curated by ChEMBL
LigandPNGBDBM50616392(CHEMBL5412341)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of recombinant human MMP2 using MOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-N2 as substrate preincubated for 10 to 15 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)