Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 8J18
TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50511002(CHEMBL4288936)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50511002(CHEMBL4288936)
Affinity DataEC50:  1.31E+3nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as inhibition of forskolin-stimulat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50511002(CHEMBL4288936)
Affinity DataEC50:  3.25E+3nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as beta-arrestin 2 recruitment meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50511002(CHEMBL4288936)
Affinity DataEC50:  1.30E+4nMAssay Description:Agonist activity at human Gialpha-coupled GPR84 expressed in baculovirus infected sf9 insect cells assessed as induction of [35S]GTPgammaS incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)