Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) for PDB: 8JD6
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50293743BDBM50293743(CHEMBL556667 | cid_836002 | N-(3-chlorophenyl)pico...)
Affinity DataEC50:  290nMAssay Description:Activity at rat mGluR4 receptor expressed in HEK293 cells assessed as effect on thallium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 4 [Q124R](Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 50293743BDBM50293743(CHEMBL556667 | cid_836002 | N-(3-chlorophenyl)pico...)
Affinity DataEC50:  295nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssayPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50293743BDBM50293743(CHEMBL556667 | cid_836002 | N-(3-chlorophenyl)pico...)
Affinity DataEC50:  330nMAssay Description:Positive allosteric modulator activity at rat mGlu4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 50293743BDBM50293743(CHEMBL556667 | cid_836002 | N-(3-chlorophenyl)pico...)
Affinity DataEC50:  1.09E+3nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssayPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 50293743BDBM50293743(CHEMBL556667 | cid_836002 | N-(3-chlorophenyl)pico...)
Affinity DataEC50:  1.10E+3nMAssay Description:Positive allosteric modulation of human mGluR4 expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium flux prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 50293743BDBM50293743(CHEMBL556667 | cid_836002 | N-(3-chlorophenyl)pico...)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at human mGlu4 receptor assessed as increase in calcium flux by Fluo-4 AM dye based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 50293743BDBM50293743(CHEMBL556667 | cid_836002 | N-(3-chlorophenyl)pico...)
Affinity DataEC50:  1.10E+3nMAssay Description:Activity at human mGluR4 receptor expressed in CHO cells assessed as effect on calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 50293743BDBM50293743(CHEMBL556667 | cid_836002 | N-(3-chlorophenyl)pico...)
Affinity DataEC50:  1.20E+3nMAssay Description:Positive allosteric modulator activity at human mGlu4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 4 [Q124R](Rat)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 50293743BDBM50293743(CHEMBL556667 | cid_836002 | N-(3-chlorophenyl)pico...)
Affinity DataEC50:  9.84E+3nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssayPDB3D3D Structure (crystal)