Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) for PDB: 8JXW
TargetHistamine H4 receptor(Human)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50191289(VUF-6884 | 7-chloro-11-(4-methylpiperazin-1-yl)-di...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistamine H4 receptor(Human)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50191289(VUF-6884 | 7-chloro-11-(4-methylpiperazin-1-yl)-di...)
Affinity DataKd:  10.7nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor transfected in SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistamine H4 receptor(Human)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50191289(VUF-6884 | 7-chloro-11-(4-methylpiperazin-1-yl)-di...)
Affinity DataKd:  13nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor transfected in SK-N-MC cells at 10 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistamine H4 receptor(Human)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50191289(VUF-6884 | 7-chloro-11-(4-methylpiperazin-1-yl)-di...)
Affinity DataKd:  22.2nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor transfected in SK-N-MC cells at 30 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistamine H4 receptor(Human)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50191289(VUF-6884 | 7-chloro-11-(4-methylpiperazin-1-yl)-di...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistamine H4 receptor(Human)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50191289(VUF-6884 | 7-chloro-11-(4-methylpiperazin-1-yl)-di...)
Affinity DataKi:  28.2nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistamine H4 receptor(Human)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50191289(VUF-6884 | 7-chloro-11-(4-methylpiperazin-1-yl)-di...)
Affinity DataKd:  72nMAssay Description:Displacement of [3H]Histamine from human histamine H4 receptor transfected in SK-N-MC cells at 100 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistamine H4 receptor(Human)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50191289(VUF-6884 | 7-chloro-11-(4-methylpiperazin-1-yl)-di...)
Affinity DataKi:  102nMAssay Description:Displacement of [3H]histamine from human histamine 4 receptor expressed in Sf9 cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)