Affinity DataIC50: 5nMAssay Description:Inhibition of gamma secretase in human MCF7 cells assessed as reduction in amyloid beta 40 after 3 days by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as notch cleavageMore data for this Ligand-Target Pair

3D Structure (crystal)