Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 8OY2
TargetCyclin-dependent kinase 2(Human)
LifeMine Therapeutics

Curated by ChEMBL
LigandPNGBDBM50645810(CHEMBL5589612)
Affinity DataIC50: 640nMAssay Description:Inhibition of CDK2 in human OVCAR-3 cells assessed as reduction in Rb phosphorylation at T821 residue treated for 4 hrs followed by drug wash-out and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 2(Human)
LifeMine Therapeutics

Curated by ChEMBL
LigandPNGBDBM50645810(CHEMBL5589612)
Affinity DataIC50: 950nMAssay Description:Inhibition of CDK2 in human OVCAR-3 cells assessed as reduction in Rb phosphorylation at T821 residue treated for 4 hrs followed by drug wash-out and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 2(Human)
LifeMine Therapeutics

Curated by ChEMBL
LigandPNGBDBM50645810(CHEMBL5589612)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CDK2 in human OVCAR-3 cells assessed as reduction in Rb phosphorylation at T821 residue measured after 120 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 2(Human)
LifeMine Therapeutics

Curated by ChEMBL
LigandPNGBDBM50645810(CHEMBL5589612)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of CDK2 in human OVCAR-3 cells assessed as reduction in Rb phosphorylation at T821 residue measured after 18 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)