Affinity DataKd: 1.5nMAssay Description:Binding affinity to recombinant human Avi-tagged wild type STING (149 to 379 residues) expressed in Escherichia coli BL21 DE3 assessed as dissociatio...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKd: 2.40nMAssay Description:Binding affinity to recombinant human wild type STING (155 to 341 residues) expressed in Escherichia coli BL21 DE3 assessed as dissociation constant ...More data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Agonist activity at human STING expressed in human THP-1 cells expressing IRF inducible SEAP reporter construct assessed as increase in interferon pr...More data for this Ligand-Target Pair
Affinity DataEC50: 540nMAssay Description:Agonist activity at human wild type STING overexpressed in STING knockout human THP1-Blue ISG cells expressing IRF inducible SEAP reporter construct ...More data for this Ligand-Target Pair
Affinity DataEC50: 4.80E+3nMAssay Description:Agonist activity at human STING expressed in mouse RAW cells expressing IRF inducible SEAP reporter construct assessed as increase in interferon prod...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at human STING in STING knockout human THP1-Blue ISG cells expressing IRF inducible SEAP reporter construct assessed as increase in ...More data for this Ligand-Target Pair
