Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 8P6W
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 21nMAssay Description:Inhibition of CDK7/cyclinH/MAT1 assessed as amount of ATP released by luciferase activity based PKLight assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 7(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 21nMAssay Description:Competitive reversible inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 7(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 21nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 7(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50347389(CHEMBL1801932)
Affinity DataIC50: 134nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)