Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 8PM9
TargetTransthyretin(Human)
Autonomous University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50620814(CHEMBL5408344)
Affinity DataKd:  14nMAssay Description:Binding affinity to TTR V122I mutant (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTransthyretin(Human)
Autonomous University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50620814(CHEMBL5408344)
Affinity DataKd:  16nMAssay Description:Binding affinity to wild-type TTR (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTransthyretin(Human)
Autonomous University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50620814(CHEMBL5408344)
Affinity DataKd:  36nMAssay Description:Binding affinity to TTR V30M mutant (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)