Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 8QZD
TargetBifunctional epoxide hydrolase 2(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50633590(CHEMBL5409600)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of recombinant human sEH using fluorogenic PHOME as substrate measured after 10 sec by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBifunctional epoxide hydrolase 2(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50633590(CHEMBL5409600)
Affinity DataIC50: 68nMAssay Description:Inhibition of sEH in IFNgamma induced human HAP1 cells assessed as reduction in kynurenine productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBifunctional epoxide hydrolase 2(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50633590(CHEMBL5409600)
Affinity DataIC50: 159nMAssay Description:Displacement of tracer from NanoLuc fused sEH in HEK293T cells assessed as decrease in BRET ratio incubated for 5 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)