Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 8R4V
TargetSerine/threonine-protein kinase SIK3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM192712(HG-9-91-01 (1))
Affinity DataIC50: 9.60nMAssay Description:Inhibition of SIK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase SIK3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM192712(HG-9-91-01 (1))
Affinity DataIC50: 9.60nMAssay Description:Inhibition of GST fused recombinant SIK3 (unknown origin) expressed in HEK293 cells ALNRTSSDSALHRRR as substrate incubated for 1 hr in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase SIK3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM192712(HG-9-91-01 (1))
Affinity DataIC50: 430nMAssay Description:Inhibition of SIK3 (unknown origin) using ALNRTSSDSALHRRR as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase SIK3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM192712(HG-9-91-01 (1))
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of GST fused recombinant SIK3 (unknown origin) in human HEK293 cells assessed as effect on CRTC3 phosphorylation at Ser162 incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)