Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 8T6D
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Relay Therapeutics

Curated by ChEMBL
LigandPNGBDBM484868(US10934302, Example 119)
Affinity DataIC50: 1nMAssay Description:Inhibition of wild-type full-length SHP2 (unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Relay Therapeutics

Curated by ChEMBL
LigandPNGBDBM484868(US10934302, Example 119)
Affinity DataIC50: 170nMAssay Description:Inhibition of full-length SHP2 E76K mutant (unknown origin) expressed in Escherichia coli BL21(DE3) using DiFMUP as substrate preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)