Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 8TRA
TargetP2X purinoceptor 7(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416603(CHEMBL1222883)
Affinity DataIC50: 251nMAssay Description:Antagonist activity at rat recombinant P2X7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2X purinoceptor 7(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416603(CHEMBL1222883)
Affinity DataIC50: 316nMAssay Description:Inhibition of rat P2X7 receptor by ethidium bromide release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2X purinoceptor 7(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416603(CHEMBL1222883)
Affinity DataKi:  510nMAssay Description:Displacement of [3H]-A-804598 from rat P2X7 receptor expressed in HEK293 cell membrane by in vitro binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2X purinoceptor 7(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50416603(CHEMBL1222883)
Affinity DataIC50: 1.90E+3nMAssay Description:Antagonist activity at rat P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced calcium-flux measured after 60 mins by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2X purinoceptor 7(Mouse)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50416603(CHEMBL1222883)
Affinity DataIC50: 2.30E+3nMAssay Description:Antagonist activity at mouse P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced calcium-flux measured after 60 mins by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)