Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) for PDB: 8VBY
TargetSodium-dependent dopamine transporter(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM22397(methyl (1R,2S,3S,5S)-3-(4-fluorophenyl)-8-methyl-8...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM22397(methyl (1R,2S,3S,5S)-3-(4-fluorophenyl)-8-methyl-8...)
Affinity DataKi:  10.4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM22397(methyl (1R,2S,3S,5S)-3-(4-fluorophenyl)-8-methyl-8...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]WIN 35428 from human DAT transiently expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM22397(methyl (1R,2S,3S,5S)-3-(4-fluorophenyl)-8-methyl-8...)
Affinity DataKi:  13nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM22397(methyl (1R,2S,3S,5S)-3-(4-fluorophenyl)-8-methyl-8...)
Affinity DataKi:  13.4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Rat)
Wake Forest University

Curated by PDSP Ki Database
LigandPNGBDBM22397(methyl (1R,2S,3S,5S)-3-(4-fluorophenyl)-8-methyl-8...)
Affinity DataKi:  27.9nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Rat)
Wake Forest University

Curated by PDSP Ki Database
LigandPNGBDBM22397(methyl (1R,2S,3S,5S)-3-(4-fluorophenyl)-8-methyl-8...)
Affinity DataKi:  31.9nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50236804(CHEMBL4066973)
Affinity DataEC50:  35nMAssay Description:Enhancing of [125I]RTI-55 binding to recombinant human DAT expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Rat)
Wake Forest University

Curated by PDSP Ki Database
LigandPNGBDBM22397(methyl (1R,2S,3S,5S)-3-(4-fluorophenyl)-8-methyl-8...)
Affinity DataKi:  44nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50236804(CHEMBL4066973)
Affinity DataEC50:  124nMAssay Description:Enhancing of [3H]mazindol binding to recombinant human DAT expressed in HEK293 cell membranes preincubated for 10 mins followed by radioligand additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50236804(CHEMBL4066973)
Affinity DataIC50: 127nMAssay Description:Inhibition of recombinant human DAT expressed in HEK293 cell membranes assessed as reduction in [3H]-DA uptake incubated for 22 mins by micro beta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Mouse)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50236804(CHEMBL4066973)
Affinity DataEC50:  810nMAssay Description:Enhancing of [125I]RTI-55 binding to mouse DAT expressed in HEK293 cells preincubated for 10 mins followed by radioligand addition measured after 90 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Mouse)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50236804(CHEMBL4066973)
Affinity DataIC50: 940nMAssay Description:Inhibition of mouse DAT expressed in HEK293 cells assessed as reduction in [3H]-DA uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM22397(methyl (1R,2S,3S,5S)-3-(4-fluorophenyl)-8-methyl-8...)
Affinity DataKi:  1.90E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2012
Entry Details
PubMedPDB3D3D Structure (crystal)