Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 8VW4
TargetE3 ubiquitin-protein ligase CBL-B(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50641996BDBM50641996(CHEMBL5567342)
Affinity DataKd:  78nMAssay Description:Binding affinity to N-terminal Avi-tagged biotinylated human Cbl-b (40 to 426 residues) expressed in Escherichia coli by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase CBL-B(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50641996BDBM50641996(CHEMBL5567342)
Affinity DataIC50: 170nMAssay Description:Inhibition of active phospho Cbl-b (unknown origin) using His-phospho ZAP70 as substrate incubated for 30 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)