Compile Data Set for Download or QSAR
Report error Found 1 Enz. Inhib. hit(s) for PDB: 8W4S
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50113739(2-{(2-Hydroxy-ethyl)-[9-isopropyl-6-(4-methoxy-ben...)
Affinity DataIC50: 230nMAssay Description:Inhibition of his-tagged recombinant human PDE5A catalytic domain (E535 to Q860 residues) expressed in Escherichia coli BL21(DE3) using [3H]-cGMP as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)