Affinity DataEC50: 740nMAssay Description:Allosteric modulator activity at human mGlu4 receptor expressed in CHO cells coexpressing Gqi5 assessed as effect on calcium fluxMore data for this Ligand-Target Pair
Affinity DataEC50: 750nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in BHK cells assessed as potentiation of glutamate-induced calcium mobilization afte...More data for this Ligand-Target Pair

3D Structure (crystal)