TargetShort transient receptor potential channel 4(Human)
University of Nebraska Medical Center
Curated by ChEMBL
University of Nebraska Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.0120nMAssay Description:Inhibition of human TRPC4 expressed in HEK293 cells assessed as reduction in sphingosine-1-phosphate-induced current at -100 mV by patch clamp assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetShort transient receptor potential channel 4(Human)
University of Nebraska Medical Center
Curated by ChEMBL
University of Nebraska Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human TRPC4 expressed in HEK293 cells assessed as reduction in sphingosine-1-phosphate-induced current at +100 mV by patch clamp assayMore data for this Ligand-Target Pair
TargetShort transient receptor potential channel 1/4(Human)
University of Nebraska Medical Center
Curated by ChEMBL
University of Nebraska Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.0330nMAssay Description:Inhibition of human TRPC4/human TRPC1 expressed in HEK293 cells assessed as reduction in englerin A-induced calcium entry incubated for 30 mins by Fl...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 1/5(Human)
University of Nebraska Medical Center
Curated by ChEMBL
University of Nebraska Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.190nMAssay Description:Inhibition of human TRPC5/human TRPC1 expressed in HEK293 cells assessed as reduction in englerin A-induced calcium entry incubated for 30 mins by Fl...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 4(Human)
University of Nebraska Medical Center
Curated by ChEMBL
University of Nebraska Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.340nMAssay Description:Inhibition of human TRPC4 expressed in HEK293 cells assessed as reduction in englerin A-induced calcium entry incubated for 30 mins by Fluo-4AM dye b...More data for this Ligand-Target Pair
