Compile Data Set for Download or QSAR
Report error Found 1 Enz. Inhib. hit(s) for PDB: 8XFD
TargetPyruvate kinase PKLR(Human)
Sitryx Therapeutics

US Patent
LigandPNGBDBM50597714(Mitapivat | Ag-348 | Pkr-in-1 | AG-348 | MITAPIVAT...)
Affinity DataEC50:  32.1nMAssay Description:Human PKLR was diluted into Assay Buffer to a final concentration of 5 pM. Enzyme-Assay Buffer mix was dispensed into 384-well shallow-well white-wal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)