Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 8XFM
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50562615BDBM50562615(CHEMBL4764756)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human recombinant MNK2 expressed in HEK293T cells incubated for 2 hrs in presence of ATP by ADP-Glo Kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50562615BDBM50562615(CHEMBL4764756)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of recombinant MNK2 (unknown origin) in presence of ATP by ADP--Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50562615BDBM50562615(CHEMBL4764756)
Affinity DataKi:  5.5nMAssay Description:ATP-competitive inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50562615BDBM50562615(CHEMBL4764756)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-fused MNK2 (1 to 465 residues) expressed in baculovirus expression system using GRSRSRSRSR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Shandong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50562615BDBM50562615(CHEMBL4764756)
Affinity DataIC50: 35nMAssay Description:Inhibition of Mnk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)