Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 8XJK
TargetProstaglandin F2-alpha receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50085910BDBM50085910(CLOPROSTENOL | CHEMBL37853 | (Z)-7-{(1R,2R,3R,5S)-...)
Affinity DataKi:  0.470nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin F2-alpha receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50085910BDBM50085910(CLOPROSTENOL | CHEMBL37853 | (Z)-7-{(1R,2R,3R,5S)-...)
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGF2-alpha from human FP-receptor expressed in CHO-KI cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin F2-alpha receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50085910BDBM50085910(CLOPROSTENOL | CHEMBL37853 | (Z)-7-{(1R,2R,3R,5S)-...)
Affinity DataIC50: 2nMAssay Description:Affinity for human Prostanoid FP receptor expressed in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin F2-alpha receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50085910BDBM50085910(CLOPROSTENOL | CHEMBL37853 | (Z)-7-{(1R,2R,3R,5S)-...)
Affinity DataEC50:  10nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human FP-receptor (% of control ligand, fluprostenol=100%)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin F2-alpha receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50085910BDBM50085910(CLOPROSTENOL | CHEMBL37853 | (Z)-7-{(1R,2R,3R,5S)-...)
Affinity DataKi:  31nMAssay Description:Inhibitory Binding constant (n=2) to Prostanoid FP receptor expressed in bovine corpus luteumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)